Skip to content. | Skip to navigation

Informatik 5
Information Systems
Prof. Dr. M. Jarke
Sections
Personal tools
You are here: Home Staff Prof. Dr. Thomas Berlage

Prof. Dr. Thomas Berlage - Theses


Master
Next-generation Sequencing Using Data Lakes - MA / BA - Open
Supervised by Prof. Dr. Thomas Berlage, Prof. Dr. Christoph Quix; Advisor(s): Dr. Sandra Geisler, Tillmann Eitelberg
NGS Pipeline on Azure Data Lake The development of next-generation sequencing (NGS) technologies at the beginning of the 21st century opened the door for revolutionary study setups which enables access to a long time closed dimension of knowledge in several fields of research like genetics, ecology and medicine. The so called “Ppipeline” is the link between different work steps and corresponding tools within the workflow when analyzing a NGS dataset. Microsoft Azure Data Lake is based on two different services. The Azure Data Lake Store allows to store different types of data in an almost unlimited size. With Azure Data Lake Analytics it’s possible to run massively parallel data transformation and processing programs massively in U-SQL, R, Python, and .NET over petabytes of data stored in the Azure Data Lake Store. In our company, we develop the system BOA , a Pipeline based on Microsoft Azure Data Lake designed for analyzing NGS datasets. In order to achieve maximum performance and optimal results, the data for the various steps are partitioned and analyzed using different algorithms. The input and output of the data within BOA is done via a user-friendly user interface. In addition, the system offers the possibility to analyze the data directly against various reference databases. The goals of this thesis are: - to evaluate different algorithms for data partitioning in the context von RNA sequences - to evaluate different algorithms in different languages (C#, R, Python) to optimize the performance in sequence alignment - to design and implement an incremental loading process of different RNA reference databases for the alignment process
Master
Design and Implementation of Data Visualization Software for High Resolution Manometry - Finished
Completed by Sivaramakrishnan, Karthika in 2007; Supervised by Prof. Dr. Thomas Berlage, Prof. Dr. Matthias Jarke; Advisor(s): Jolande Koobs-Blankestijn (Medical Measurement Systems, Enschede, the Netherlands)
Master
Accessibility Analysis of Dynamically Changing Online Applications - Finished
Completed by Edupuganti, Naveen in 2007; Supervised by Prof. Dr. Matthias Jarke, Prof. Dr. Thomas Berlage; Advisor(s): Dr. Carlos A. Velasco
Master
Building Semantic Model for Common Document Formats with Optimized Searching - Finished
Completed by Valluripalli, Phanikumar in 2007; Supervised by Prof. Dr. Matthias Jarke, Prof. Dr. Thomas Berlage; Advisor(s): Dr. Carlos A. Velasco
Master
Incorporating eAccessibility in the workflow and design process of Content Management Systems - Finished
Completed by Ephram, Robina in 2006; Supervised by Prof. Dr. Matthias Jarke, Prof. Dr. Thomas Berlage; Advisor(s): Dr. Carlos A. Velasco
Master
Tracking of Server Software used During Clinical Study - Finished
Completed by AnilKumar, Edala in 2006; Supervised by Prof. Dr. Matthias Jarke, Prof. Dr. Thomas Berlage
Diplom