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Informatik 5
Information Systems
Prof. Dr. M. Jarke
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Prof. Dr. M. Jarke
RWTH Aachen
Informatik 5
Ahornstr. 55
D-52056 Aachen
Tel +49/241/8021501
Fax +49/241/8022321

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Classification of Cancer with methylation aware motifs

Thesis type
  • Bachelor
Status Running
Proposal on 01. Apr 2019 00:00
Proposal room Seminarraum I5
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DNA methylation data has become a popular choice as features for cancer classification tasks. However, a big problem arising here is its high dimensionality in combination with the usually small amount of available samples. Therefore, we created lower-dimensional meta-features that take the effects of the altered DNA methylation pattern on the binding affinity of human Transcription Factors into account. Their performance is evaluated in this thesis.

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