{"id":5484,"date":"2024-10-17T13:20:07","date_gmt":"2024-10-17T11:20:07","guid":{"rendered":"https:\/\/dbis.rwth-aachen.de\/dbis\/?p=5484"},"modified":"2025-01-27T16:25:25","modified_gmt":"2025-01-27T15:25:25","slug":"single-cell-centric-biomedical-foundation-models-for-cancer","status":"publish","type":"post","link":"https:\/\/dbis.rwth-aachen.de\/dbis\/index.php\/2024\/single-cell-centric-biomedical-foundation-models-for-cancer\/","title":{"rendered":"Single-Cell Centric Biomedical Foundation Models for Cancer"},"content":{"rendered":"\n<p>This thesis aims to develop a single-cell-centric biomedical foundation model that leverages the capabilities of generative pre-trained transformers to enhance the analysis of single-cell RNA data. The model will address critical tasks in single-cell biology, such as cell-type annotation, perturbation prediction, identification of pathogenic cells, and gene network inference.<\/p>\n\n\n\n<p>This thesis is co-supervised by Sikander Hayat and Rafael Kramann, Department of Medicine II, University Hospital Aachen.<\/p>\n\n\n\n<p>Please send your application to Yongli Mou, M.Sc. (<a href=\"mailto:mou@dbis.rwth-aachen.de\">mou@dbis.rwth-aachen.de<\/a>) and CC. Dr. Sikander Hayat (<a href=\"mailto:shayat@ukaachen.de\">shayat@ukaachen.de<\/a>)<\/p>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>This thesis aims to develop a single-cell-centric biomedical foundation model that leverages the capabilities of generative pre-trained transformers to enhance the analysis of single-cell RNA data. The model will address critical tasks in single-cell biology, such as cell-type annotation, perturbation prediction, identification of pathogenic cells, and gene network inference. This thesis is co-supervised by Sikander [&hellip;]<\/p>\n","protected":false},"author":19,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[21],"tags":[],"class_list":["post-5484","post","type-post","status-publish","format-standard","hentry","category-thesis"],"acf":[],"_links":{"self":[{"href":"https:\/\/dbis.rwth-aachen.de\/dbis\/index.php\/wp-json\/wp\/v2\/posts\/5484","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/dbis.rwth-aachen.de\/dbis\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/dbis.rwth-aachen.de\/dbis\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/dbis.rwth-aachen.de\/dbis\/index.php\/wp-json\/wp\/v2\/users\/19"}],"replies":[{"embeddable":true,"href":"https:\/\/dbis.rwth-aachen.de\/dbis\/index.php\/wp-json\/wp\/v2\/comments?post=5484"}],"version-history":[{"count":10,"href":"https:\/\/dbis.rwth-aachen.de\/dbis\/index.php\/wp-json\/wp\/v2\/posts\/5484\/revisions"}],"predecessor-version":[{"id":5819,"href":"https:\/\/dbis.rwth-aachen.de\/dbis\/index.php\/wp-json\/wp\/v2\/posts\/5484\/revisions\/5819"}],"wp:attachment":[{"href":"https:\/\/dbis.rwth-aachen.de\/dbis\/index.php\/wp-json\/wp\/v2\/media?parent=5484"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/dbis.rwth-aachen.de\/dbis\/index.php\/wp-json\/wp\/v2\/categories?post=5484"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/dbis.rwth-aachen.de\/dbis\/index.php\/wp-json\/wp\/v2\/tags?post=5484"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}